Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 4 Reviews
8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
667 mcg DFE (400 mcg Folic Acid)
167%
Calcium (as Calcium Carbonate)
100 mg
8%

Top Medical Research Studies

7
Folic acid reduces cholesterol risk
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.

Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.

Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.

Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Read More
8
Cholesterol reduction in children studied
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.

Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.

We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.

Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Read More

Most Useful Reviews

9
Supports heart health
3 people found this helpful
Folic acid is an essential B vitamin (B9) that contributes to heart health. Regular intake reduces the risk of stroke and cardiovascular disorders, normalises blood pressure, and lowers high cholesterol. It’s also vital during pregnancy for cell creation and maintaining a healthy state.
Read More
6
Convenient dosage
1 people found this helpful
The packaging is convenient with a good price and small tablet size. I split the tablet since I need 200 mcg, not 400 mcg, which makes it last longer. I take it for high cholesterol, as folic acid is involved in its metabolism. I will assess the results after 3 months.
Read More
7.5
Improves heart health
4 people found this helpful
Supplementing with folate-based supplements, like folic acid, may enhance heart health and lower high cholesterol risk factors. These supplements can improve blood flow and may assist those with diabetes in controlling blood sugar and reducing complications. I will give it a try!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
  • All Researches
8
Cholesterol reduction in children studied
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.

Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.

We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.

Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Read More
7
Folic acid reduces cholesterol risk
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.

Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.

Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.

Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Read More

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Supports heart health
3 people found this helpful
Folic acid is an essential B vitamin (B9) that contributes to heart health. Regular intake reduces the risk of stroke and cardiovascular disorders, normalises blood pressure, and lowers high cholesterol. It’s also vital during pregnancy for cell creation and maintaining a healthy state.
Read More
6
Convenient dosage
1 people found this helpful
The packaging is convenient with a good price and small tablet size. I split the tablet since I need 200 mcg, not 400 mcg, which makes it last longer. I take it for high cholesterol, as folic acid is involved in its metabolism. I will assess the results after 3 months.
Read More
7.5
Improves heart health
4 people found this helpful
Supplementing with folate-based supplements, like folic acid, may enhance heart health and lower high cholesterol risk factors. These supplements can improve blood flow and may assist those with diabetes in controlling blood sugar and reducing complications. I will give it a try!
Read More
2
High quality, ineffective
Good product with high quality and a large quantity but it doesn’t work for me.
Read More

Frequently Asked Questions

6
Convenient dosage
1 people found this helpful
The packaging is convenient with a good price and small tablet size. I split the tablet since I need 200 mcg, not 400 mcg, which makes it last longer. I take it for high cholesterol, as folic acid is involved in its metabolism. I will assess the results after 3 months.
7.5
Improves heart health
4 people found this helpful
Supplementing with folate-based supplements, like folic acid, may enhance heart health and lower high cholesterol risk factors. These supplements can improve blood flow and may assist those with diabetes in controlling blood sugar and reducing complications. I will give it a try!
2
High quality, ineffective
Good product with high quality and a large quantity but it doesn’t work for me.
9
Supports heart health
3 people found this helpful
Folic acid is an essential B vitamin (B9) that contributes to heart health. Regular intake reduces the risk of stroke and cardiovascular disorders, normalises blood pressure, and lowers high cholesterol. It’s also vital during pregnancy for cell creation and maintaining a healthy state.
8
Cholesterol reduction in children studied
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.

Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.

We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.

Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
7
Folic acid reduces cholesterol risk
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.

Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.

Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.

Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.

References

  1. Garoufi A, Papadaki M, Kalogiannis M, Zerva U, Charakida M, et al. Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia. Biomolecules. 2024;14. 10.3390/biom14121608
  2. Qi J, Wu H, Chen H, Han W. Genetically predicted lipid traits mediate the association between folic acid and atherosclerosis. Sci Rep. 2024;14:19052. 10.1038/s41598-024-69728-2
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